I personally feel that Juvéderm Ultra Plus and Perlane are both excellent products that can do a wonderful job of filling in deeper facial wrinkles or folds. Both products are exceptionally safe and I have extensive experience using both of them. Regarding a preference, I really do not have much of one as I have had excellent results with both. They both are very similar in their injection techniques. Juvéderm Ultra Plus may be slightly softer than Perlane and some feel that it may last slightly longer though, at Quintessa Medical Spa, we actually did a head-to-head comparison between Juvéderm Ultra Plus and Perlane, and though we had a very limited number of patients, we did not see any significant difference between the two products.
